More crucially , the country has developed a serious costs problem .

更为关键的是，该国出现了严峻的成本问题。

Investment policy has paid too little attention to these crucially important long-run trends .

目前的投资策略对这些至关重要的长期趋势关注得太少。

Just as crucially , its hunt for resources is extending in new directions .

同样重要的是，中国对于资源的猎取正向着新的方向蔓延。

Resistance remains most crucially in berlin .

阻力也依然存在，最主要的是来自德国。

And , crucially , a lack of insulin or insulin resistance is connected both to amyloid protein regulation and to the modification of tau proteins , which can cause tangles .

而且，至关紧要的是，缺乏胰岛素或产生胰岛素抵抗都与类淀粉蛋白的调节有关，还与能导致神经纤维缠结的tau蛋白的变性有关。