Newton st loe 's oldest buildings date from the 15th century , and it has changed little in recent years .

牛顿圣洛最古老的建筑始建于公元15世纪，近年来几乎没有变化。

Barbara loe fisher , co-founder and president of the national vaccine information center , which supports more research into the safety of vaccinations , said autism is just one concern linked to vaccines .

国家疫苗信息中心的创始人之一兼董事长芭芭拉费舍尔支持在疫苗安全方面投入更多的研究，并且表示自闭症问题仅仅是与疫苗有关的问题之一。

According to iain loe of camra , a group dedicated to promoting good beer , 99 commercial breweries opened in britainin the yearto june 2010 , boosting the total to 840 .

该组织的iainloe指出，从2010年7月至今年英国有99家商业啤酒厂开张，境内的啤酒厂总数达到840家。