His words are making me squirm in my chair .

他所说的话让坐着的我感到局促不安。

I doubt it : in my experience it is hard to squirm and listen at the same time .

我对此表示怀疑：据我的经验，我很难在局促不安的同时还能做到专心倾听。

Telling someone that they are useless is a miserable thing to do because they will get upset , and you will squirm and feel really beastly .

对某人说他一无是处，是一种极其糟糕的经历，因为他会难过，而你会感到难为情，觉得自己真是混蛋。