A：Can I help you?
      能为您效劳吗？

B：Yes, is (Mr. Smith/ the director/ the manager) in his office?
      哦，（史密斯先生/主管/经理）在办公室吗？

A：Is Mr. Smith in his office?
      史密斯先生在办公室吗？

B：I’m sorry. He’s (in a meeting/ not at his desk right now/ out).
      抱歉。他（正在开会/不在位子上/出去了）。

A：Never trust your secrets to Bob.
      别向鲍勃吐露秘密。

B：I think he’s kind and honest.
      我倒认为他为人不错，挺诚实的。

A：He’s the kind of person who do anything to save his own skin.
      他是那种为了保全自己什么都肯做的人。

B：I don’t agree with you.
      我不能同意你的看法。

1. 他的;（指雄性动物）它的
    You use his to indicate that something belongs or relates to a man, boy, or male animal.

    e.g. Brian splashed water on his face, then brushed his teeth...
           布赖恩用水冲了把脸，然后刷牙。
    e.g. He spent a large part of his career in Hollywood...
           他的职业生涯中有很长一段时间是在好莱坞度过的。

2. （书面英语中泛指人）他的，她的（有些人不喜欢这种说法，更倾向于使用 his or her 或 their）
    In written English, his is sometimes used to refer to a person without saying whether that person is a man or a woman. Some people dislike this use and prefer to use 'his or her' or 'their'.

    e.g. Formerly, the relations between a teacher and his pupils were dominated by fear on the part of the pupils...
           以往的师生关系主要是学生惧怕老师。
    e.g. Everyone should receive a fair price for the product of his labour.
           每个人都应该按劳所得。

3. （一些宗教中指）上帝
    In some religions, His is used to refer to God.

    e.g. ...humble faith in God, and trust in His Church.
           对上帝的谦卑信仰和对教会的信任